Features
Composed of dobule-layer PES membrane
Extensive chemical compatibility
High dirt holding capacity
Low protein binding
Applications
Pre-filtration of cell culture medium
Buffer filtration
Pre-filtration of terminal products
Pre-column/ultra-filtration protection
Operating Conditions
Max. Temperature | 80°C |
Max. Differential Pressure | 0.55 MPa / 25°C |
Materials of Construction
Filter Type | Bricap C/D/L/T | Cartridge |
Membrane | Polyvinylidene fluoride (PVDF) | Polyvinylidene fluoride (PVDF) |
Core/Cage/End Cap | Polypropylene (PP) | Polypropylene (PP) |
Capsule Shell | Polypropylene (PP) | - |
O-ring | - | Silicone/EPDM/ Viton/PTFE |
Capsule Vent O-ring | Silicone | - |
Removal Ratings | 1.0 + 0.45 μm |
Biological Safety
Bio-compatibility | Meet the requirement of USP<87>In Vitro Cytotoxicity Test; Meet the criteria of the USP<88>Biological Reactivity Test for Class VI-121°C plastics |
Endotoxins | < 0.25 EU/ml |
Effective Filtration Area
BriScale A50 | Bricap C/D | Bricap L | Bricap T | Cartridge |
A50: 20 cm² | C01: 180 cm² | L02: 0.12 m² | T10: 0.55 m² | 5" : 0.28 m² |
C02: 420 cm² | L03: 0.16 m² | T20: 1.1 m² | 10" : 0.55 m² | |
C03: 660 cm² | L05: 0.28 m² | T30: 1.65 m² | 20" : 1.1 m² | |
D01: 350 cm² | L10: 0.55 m² | 30" : 1.65 m² | ||
L20: 1.1 m² | 40" : 2.2 m² | |||
L30: 1.65 m² |
Sterilization Capability
Sterilization Method/Filter Format | BriScale Disc, Bricale C/ L / T | Bricap D | Cartridge |
Gamma-irradiation | 25-45 Kgy | / | / |
Autoclave (126°C) applies only to Gamma-compatible package | 5 cycle, 30min | / | / |
Autoclave (130°C) applies only to Atoclave package | 25 cycle, 30min | 25 cycle, 30min | 25 cycle, 30min |
SIP (135°C) applies only to cartridge | / | / | 25 cycle, 30min |