Features
High flow rates
Low protein binding
Efficient bacteria and particulate retention
Applications
Sterilize filtration of cell culture medium
Ophthalmic solution
Buffer filtration
Filtration of cell culture medium
Filtration of blood products/serums
Sterile filtration of intermediate products
Pre-column / ultra-filtration protection
Sterile filtration of terminal products
Filtration of colloids / Viscous liquids
Operating Conditions
Max. Temperature | 80°C |
Max. Differential Pressure | 0.55 MPa / 25°C |
Materials of Construction
Filter Type | Bricap C/D/L/T | Cartridge |
Membrane | Polyvinylidene fluoride (PVDF) | Polyvinylidene fluoride (PVDF) |
Core/Cage/End Cap | Polypropylene (PP) | Polypropylene (PP) |
Capsule Shell | Polypropylene (PP) | - |
O-ring | - | Silicone/EPDM/Viton/PTFE |
Capsule Vent O-ring | Silicone | - |
Removal Ratings | 0.2μm/ 0.2+0.1μm/ 0.45+0.2μm/ 0.65+0.2μm |
Biological Safety
Bio-compatibility | Meet the requirement of USP<87>In Vitro Cytotoxicity Test; Meet the criteria of the USP<88>Biological Reactivity Test for Class VI-121°C plastics |
Endotoxins | < 0.25 EU/ml |
Effective Filtration Area
BriScale A50 | Bricap C/D | Bricap L | Bricap T | Cartridge |
A50: 20 cm² | C01: 180 cm² | L02: 0.12 m² | T10: 0.55 m² | 5" : 0.28 m² |
C02: 420 cm² | L03: 0.16 m² | T20: 1.1 m² | 10" : 0.55 m² | |
C03: 660 cm² | L05: 0.28 m² | T30: 1.65 m² | 20" : 1.1 m² | |
D01: 350 cm² | L10: 0.55 m² | 30" : 1.65 m² | ||
L20: 1.1 m² | 40" : 2.2 m² | |||
L30: 1.65 m² |
Sterilization Capability
Sterilization Method/Filter Format | BriScale Disc, Bricale C/ L / T | Bricap D | Cartridge |
Gamma-irradiation | 25-45 Kgy | / | / |
Autoclave (126°C) applies only to Gamma-compatible package | 5 cycle, 30min | / | / |
Autoclave (130°C) applies only to Atoclave package | 25 cycle, 30min | 25 cycle, 30min | 25 cycle, 30min |
SIP (135°C) applies only to cartridge | / | / | 25 cycle, 30min |